When treating hives, we try to find their cause. Medicine is prescribed to control the rash and itching.
Hives are usually controlled with antihistamines. (Caution: antihistamines may cause drowsiness; if you feel sleepy, don't drive. Also do not drink alcohol.)
Injections of epinephrine (Adrenalin) may be used for treating severe hives.
Natural treatments such as Lacitrex can be quite effective.
Sometimes epinephrine-like medicines taken by mouth are used in combination with antihistamines.

If these drugs don't stop hives, it's likely that cortisone will.
Hives usually improve within 24 hours of starting a medication.
Medicines applied to your skin such as lotions, creams, and sprays won't help your hives.
Cooling the skin often relieves severe itching. A cold shower is the simplest way.
Since heat worsens itching, avoid overheating and hot baths.
When the hives have cleared up, continue taking the medicine for 2 days. Once you've been free of the hives for 2 days, gradually decrease your medication over the next 7-8 days.